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antibody anti-syntaxin-1a  (Synaptic Systems)


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    Synaptic Systems antibody anti-syntaxin-1a
    Antibody Anti Syntaxin 1a, supplied by Synaptic Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/antibody+anti-syntaxin-1a/anti+stx1a/pmc12148328-19-2-7
    Average 90 stars, based on 1 article reviews
    antibody anti-syntaxin-1a - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    other:

    Article Title: Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice
    Article Snippet: Antibody , anti-Syntaxin-1a (Stx1a; rabbit monoclonal) , Synaptic Systems , Cat#: 110 118 , WB (1:5000).



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    Image Search Results


    ( A ) Overview of the approach adopted for the generation of the EpiPred model, including the input datasets (blue) and the functional testing of the EpiPred predictions using three biochemical assays (stability, abundance, solubility) and STX1 interaction in an overexpression model system (yellow). ( B ) Comparison of area under the receiver operator curve (AUROC) for EpiPred and a subset of high-performing globally-trained VEPs across the full truth set. ( C ) EpiPred Probability of PLP (EpiPred-P PLP ) score distributions in the full truth set separated by class as well as the full set of VUS. EpiPred-P PLP scores of 1 suggest pathogenicity, while scores of 0 suggest neutrality ( D ) EpiPred-P PLP output for known PLP and BLB variants used in the truth set mapped onto hSTXBP1 predicted structure (AlphaFold structure: AF-P61764-F1-model_v4), EpiPred-P PLP scores close to 1 are shown in purple, while scores close to zero appear in green.

    Journal: bioRxiv

    Article Title: EpiPred: A gene-specific machine learning model for classifying missense variants in the epilepsy-related gene STXBP1

    doi: 10.1101/2025.08.09.669488

    Figure Lengend Snippet: ( A ) Overview of the approach adopted for the generation of the EpiPred model, including the input datasets (blue) and the functional testing of the EpiPred predictions using three biochemical assays (stability, abundance, solubility) and STX1 interaction in an overexpression model system (yellow). ( B ) Comparison of area under the receiver operator curve (AUROC) for EpiPred and a subset of high-performing globally-trained VEPs across the full truth set. ( C ) EpiPred Probability of PLP (EpiPred-P PLP ) score distributions in the full truth set separated by class as well as the full set of VUS. EpiPred-P PLP scores of 1 suggest pathogenicity, while scores of 0 suggest neutrality ( D ) EpiPred-P PLP output for known PLP and BLB variants used in the truth set mapped onto hSTXBP1 predicted structure (AlphaFold structure: AF-P61764-F1-model_v4), EpiPred-P PLP scores close to 1 are shown in purple, while scores close to zero appear in green.

    Article Snippet: Following SDS-PAGE and transfer to PVDF membrane, samples were probed with anti-STX1 antibody (1:1000, 18572, Cell Signaling Technology).

    Techniques: Functional Assay, Solubility, Over Expression, Comparison

    Data from representative western blots (left) and quantification (right) are plotted for the WT STXBP1 and twenty missense variants. Each assay is plotted separately: (A) Abundance, ( B ) Stability, ( C ) Solubility, and ( D ) STX1 PPI. Scores are normalized to the WT reference allele score. The quantified data is sorted, left to right, by EpiPred-P PLP score from lowest (likely benign) to highest (likely pathogenic) and colored by class (wildtype, PLP, BLB, VUS predicted PLP/BLB). n=3, * p-value < 0.05, all raw data and p-values in Table S5,6 .

    Journal: bioRxiv

    Article Title: EpiPred: A gene-specific machine learning model for classifying missense variants in the epilepsy-related gene STXBP1

    doi: 10.1101/2025.08.09.669488

    Figure Lengend Snippet: Data from representative western blots (left) and quantification (right) are plotted for the WT STXBP1 and twenty missense variants. Each assay is plotted separately: (A) Abundance, ( B ) Stability, ( C ) Solubility, and ( D ) STX1 PPI. Scores are normalized to the WT reference allele score. The quantified data is sorted, left to right, by EpiPred-P PLP score from lowest (likely benign) to highest (likely pathogenic) and colored by class (wildtype, PLP, BLB, VUS predicted PLP/BLB). n=3, * p-value < 0.05, all raw data and p-values in Table S5,6 .

    Article Snippet: Following SDS-PAGE and transfer to PVDF membrane, samples were probed with anti-STX1 antibody (1:1000, 18572, Cell Signaling Technology).

    Techniques: Western Blot, Solubility